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Florida Medical Entomology Laboratory

Florida Medical Entomology Laboratory

Dr. Cynthia Lord

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Cynthia Lord

Associate Professor

Population Modelling
clord@ufl.edu

The goal of my research program is to improve our understanding of disease transmission, particularly for vector-borne diseases. With an improved understanding of transmission, we are better able to predict outbreaks or the consequences of invasion of new pathogens or vectors, and are also better able to develop control strategies.

My laboratory uses mathematical and computer modeling to investigate questions about the ecology and epidemiology of pathogens. A major research project is the epidemiology of West Nile virus in Florida. In this project, we are trying to better understand the interaction of bird and mosquito species in transmission. Models are exploring the role of different bird and mosquito species in invasion of new areas and the transmission dynamics. Collaborative studies in the lab and field have investigated the biological and environmental factors that affect transmission

Ecological interactions such as competition can also play a role in disease transmission. Human activity like pesticide application may have effects on transmission beyond just changing mosquito numbers. We are modeling these interactions to explore how competition and pesticide use affects disease transmission. Associated collaborations are measuring parameters for the detailed relationships between aspects of transmission and competition or pesticide exposure. We are also using models and field studies to develop guidelines for methods of mosquito control that do not rely on pesticides, such as barriers of mosquito traps. Mosquito control districts need information about how to design these barriers for different species or environmental conditions. Other projects in my laboratory include the population dynamics of the black-legged tick in south Florida and modeling transmission dynamics of canine influenza in different dog populations.

A recent interest in my laboratory is how processes at one scale influence processes at other scales. We need to better understand these links to predict how differences in climate and ecology affect epidemiology. Are different pathways in the mosquito infection process critical to predicting outbreaks, or is estimating the average infection rate sufficient? Does the presence of a mosquito predator alter the population growth in a different way than changes in food availability, and does this affect the ability of the mosquitoes to transmit disease? Information is becoming available at different scales at an increasing rate, and we need to study how to integrate this to better predict or control disease. We are using models at different scales to investigate these types of questions.

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Cynthia Lord

Associate Professor

Population Modelling
clord@ufl.edu

  • Ph.D. 1991 Princeton University, Ecology and Evolutionary Biology
  • M.A. 1988 Princeton University, Biology
  • B.S. 1983 University of Vermont, Zoology
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Cynthia Lord

Associate Professor

Population Modelling
clord@ufl.edu

 

Selected Publications

  • Richards, S.L., S.L. Anderson, C.C. Lord, and W.J. Tabachnick. 2011. Effects of virus dose and incubation period on Culex nigripalpus (Diptera: Culicidae) vector competence for West Nile virus. Vector-borne Zoon. Dis, . 11: 1487-1491.
  • Lord, C. C. 2010. The effect of multiple vectors on arbovirus transmission. Israel J. Ecol. Evol., 55: 371-392.
  • Bustamante, D. M., and C. C. Lord. 2010. Sources of error in the estimation of mosquito infection rates used to assess risk of arbovirus transmission. Am. J. Trop. Med. Hyg. 82: 1172-1184.
  • Richards, S. L., C. C. Lord, K. Pesko, and W. J. Tabachnick. 2009. Environmental and biological factors influencing Culex pipiens quinquesciatus Say (Diptera: Culicidae) vector competence for Saint Louis encephalitis virus. Am. J. Trop. Med. Hyg 81: 264-272.
  • McCann, S. M., J. F. Day, S. Allan, and C. C. Lord. 2009. Age modifies effects of body size on fecundity in Culex quinquefasciatus Say (Diptera: Culicidae). J. Vector Ecol. 34: 174-181.
  • Vitek, C. J., S. L. Richards, C. N. Mores, J. F. Day, and C. C. Lord. 2008. Arbovirus transmission by Culex nigripalpus in Florida, 2005. J. Med. Entomol 45: 483-493.
  • Lord, C. C. 2007. Modeling and biological control of mosquitoes. AMCA Technical Bulletin 7, eds. T. Floore and J. Becnel.
  • Lord, C. C., C. R. Rutledge and W. J. Tabachnick. 2006. Relationships between host viremia and vector susceptibility for arboviruses. J. Med. Entomol. 43: 623-630
  • Lord, C. C. 2004. Insect seasonality and behaviour in models of vector-borne disease. Physiol. Entomol. 29: 214-222.
  • Rutledge, C. R., J. F. Day, C. C. Lord, L. M. Stark and W. J. Tabachnick. 2003. West Nile virus infection rates in Culex nigripalpus (Diptera: Culicidae) do not reflect transmission rates in Florida. J. Med. Entomol. 40: 253 258
  • Lord, C. C. and W. J. Tabachnick. 2002. The influence of non-systemic transmission on the epidemiology of insect borne arboviruses: a case study of vesicular stomatitis epidemiology in the western U. S. J. Med. Entomol. 39: 417-426.
  • Lord, C. C. and J. F. Day. 2001. Simulation studies of St. Louis encephalitis in south Florida. Vector-borne and Zoonotic Diseases 1: 299-315.
  • Lord, C. C. and J. F. Day. 2001. The impact of bird mortality: simulation studies of St. Louis encephalitis and West Nile viruses. Vector-borne and Zoonotic Diseases 1: 317-329.
  • Lord, C. C., P. S. Mellor, G. Venter, J. Pasewa & M. E. J. Woolhouse. 2002. The basic reproduction number and transmission patterns of African horse sickness and equine encephalosis viruses in South African donkeys. Epidemiol. Infect. 128: 265-275.
  • Lord, C. C. and J. F. Day. 2000. First record of Amblyomma auricularium (Acari: Ixodidae) in the United States. J. Med. Entomol. 37: 977-78.
  • Lord, C. C., B. J. H. Barnard, K. Day, J. W. Hargrove, J. J. McNamara, R. Paul, K. Trenholm & M. E. J. Woolhouse. 1999. Aggregation and distribution of strains in microparasites. Phil. Trans. Roy. Soc. B. 354: 799-807
  • Lord, C. C. & M. Baylis. 1999. Estimation of survival rates in haematophagous insects. Med. Vet. Entomol. 13: 225 233
  • Lord, C. C., M. E. J. Woolhouse and B. J. Barnard. 1997. Transmission and distribution of virus serotypes: African horse sickness in zebra. Epidemiol. Infect. 118: 43-50.
  • Lord, C. C., M. E. J. Woolhouse, P. Rawlings and P. S. Mellor. 1996. Simulation studies of African horse sickness and Culicoides imicola (Diptera: Ceratopogonidae). J. Med. Entomol. 33: 328-338.
  • Lord, C. C., M. E. J. Woolhouse, J. A. P. Heesterbeek and P. S. Mellor. 1996. Vector-borne disease and the basic reproduction number: a case study of African Horse sickness. Med. Vet. Entomol. 10: 19-28.
  • Lord, C. C. 1995. Local variation in the abundance of nymphal Ixodes scapularis (Acari: Ixodidae) in New Jersey. J. Med. Entomol. 35: 66-70.
  • Lord, C. C. 1992. Nymphal Ixodes dammini: models of the temporal abundance pattern. Int. J. Parasitol. 22: 759 765
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Cynthia Lord

Associate Professor

Population Modelling
clord@ufl.edu

Grants

  • 2011-2012 FL DACS: How does larval habitat distribution affect non-pesticide control?
  • 2011-2012 FL DACS: Improving Efficacy of Pesticide Control by Understanding its Relation to Density-dependence in Mosquito Disease Vectors.
  • 2009-2011 Canine Health Foundation: Understanding the dynamics of canine influenza virus transmission in dog populations and intervention strategies for reducing transmission.
  • 2009-2011 FL DACS: Improving non-pesticide control by identifying key factors in the success of barrier trapping.
  • 2007 FL DACS: Enhanced surveillance of arboviruses in Florida (co-investigator)
  • 2004-2011 NIH Competitive Renewal: Models and empirical studies of arboviruses 2003 FL DACS: Flight times of Culex nigripalpus (co-investigator)
  • 2001 FL DACS: Aerial adulticiding (co-investigator) 2000 FL DACS: Survival of Culex nigripalpus
  • 2000 FL DACS: Surveillance of St. Louis Encephalitis (co-investigator) 1998-
  • 2004 NIH FIRST Grant: Modeling St. Louis Encephalitis