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Florida Medical Entomology Laboratory

Florida Medical Entomology Laboratory

Dr. Nathan Burkett-Cadena

Nathan Burkett-Cadena

Assistant Professor

Mosquito Ecology - Biology of Disease Hosts
nburkettcadena@ufl.edu

Vector-borne disease ecology is an interdisciplinary science that seeks to understand the combination of biological, geological and climatological factors that produce environments conducive to the amplification and spillover of vector-borne pathogens. The biology and ecology of vertebrate host animals (mainly birds and rodents) and vectors (mosquitoes, ticks, lice, fleas and others) have profound influence on the transmission of viruses and protozoans that impact humans as well as non-human animals. Contact between the vertebrate hosts and vectors are driven by their ecology (the microhabitats they inhabit, the time of day they forage, their host or prey preference) and the quantity of host-vector contacts is profoundly important in driving vector-borne disease transmission. Eastern equine encephalitis virus, for example, is a deadly mosquito-borne virus that replicates well in some birds, but not in others. However, being a competent host for the virus is only one factor determining whether or not a given bird species is important for virus transmission in nature. If a bird species that supports virus replication is "avoided" (not fed upon) by the mosquitoes in the area, then it contributes little to the spread of the virus. So why is one bird species avoided by mosquitoes, and another "preferred"? Some avoided birds actively defend against attacking mosquitoes. Others may nest or roost high above the height that the mosquitoes search for hosts. A major focus of my research is centered on investigating host-vector ecology: quantifying the relationships and determining why different species of host animals (birds, mammals, reptiles and amphibians) are preferred or avoided by different vector species. The overarching goal is to understand how these interactions drive the transmission of vector-borne pathogens.

My research has focused on diverse vector-borne disease systems including river blindness, eastern equine encephalitis virus, West Nile virus, epizootic, Everglades virus and epizootic hemorrhagic disease virus. Current projects focus on ecology of eastern equine encephalitis virus, West Nile virus, epizootic, Everglades virus and epizootic hemorrhagic disease virus. Students and postdocs in my program receive training and experience in field techniques involving vectors and vertebrate hosts, laboratory techniques including morphological and molecular identification of vectors and hosts, and analysis if field and laboratory data.

Nathan Burkett-Cadena

Assistant Professor

Mosquito Ecology - Biology of Disease Hosts
nburkettcadena@ufl.edu

  • Ph.D., Entomology, Auburn University, 2010
  • M.S., Entomology, Auburn University, 2005
  • B.S., Biology, University of South Alabama, 2001

Nathan Burkett-Cadena

Assistant Professor

Mosquito Ecology - Biology of Disease Hosts
nburkettcadena@ufl.edu

Representative Publications

    1. Sloyer KE, Acevedo C, Runkel AE, Burkett-Cadena ND. (2019) Host Associations Of Biting Midges (Diptera: Ceratopogonidae: Culicoides) Near Sentinel Chicken Surveillance Locations In Florida, USA. J Am Mosq Control Assoc Sep;35(3):200-206
    2. Erram D, Burkett-Cadena N. (2019) Laboratory Rearing of Culicoides stellifer (Diptera: Ceratopogonidae), a Suspected Vector of Orbiviruses in the United States. J Med Entomol Oct 11
    3. Rojas-Araya D, Alto BW, Burkett-Cadena N, Cummings DA. (2019) Detection of Fluorescent Powders and Their Effect on Survival and Recapture of Aedes aegypti (Diptera: Culicidae). J Med Entomol Oct 6
    4. Reeves LE, Hoyer I, Acevedo C, Burkett-Cadena ND. (2019) Host Associations of Culex (Melanoconion) atratus (Diptera: Culicidae) and Culex (Melanoconion) pilosus from Florida, USA. Insects Aug 3;10(8)
    5. Erram D, Blosser EM, Burkett-Cadena N. (2019) Habitat associations of Culicoides species (Diptera: Ceratopogonidae) abundant on a commercial cervid farm in Florida, USA. Parasit Vectors Jul 26;12(1):367
    6. McGregor BL, Sloyer KE, Sayler KA, Goodfriend O, Krauer JMC, Acevedo C, Zhang X, Mathias D, Wisely SM, Burkett-Cadena ND. (2019) Field data implicating Culicoides stellifer and Culicoides venustus (Diptera: Ceratopogonidae) as vectors of epizootic hemorrhagic disease virus. Parasit Vectors May 23;12(1):258
    7. Hoyer IJ, Acevedo C, Wiggins K, Alto BW, Burkett-Cadena ND. (2019) Patterns of Abundance, Host Use, and Everglades Virus Infection in Culex (Melanoconion) cedecei Mosquitoes, Florida, USA. Emerg Infect Dis Jun;25(6):1093-1100
    8. Glushakova LG, Alto BW, Kim MS, Hutter D, Bradley A, Bradley KM, Burkett-Cadena ND, Benner SA. (2019) Multiplexed kit based on Luminex technology and achievements in synthetic biology discriminates Zika, chikungunya, and dengue viruses in mosquitoes. BMC Infect Dis May 14;19(1):418
    9. McGregor BL, Erram D, Acevedo C, Alto BW, Burkett-Cadena ND. (2019) Vector Competence of Culicoides sonorensis (Diptera: Ceratopogonidae) for Epizootic Hemorrhagic Disease Virus Serotype 2 Strains from Canada and Florida. Viruses Apr 22;11(4)
    10. Sloyer KE, Burkett-Cadena ND, Yang A, Corn JL, Vigil SL, McGregor BL, Wisely SM, Blackburn JK. (2019) Ecological niche modeling the potential geographic distribution of four Culicoides species of veterinary significance in Florida, USA. PLoS One Feb 15;14(2):e0206648
    11. Efstathion CA, Burkett-Cadena ND, Kern WH Jr. (2019) Prefledging Mortality and the Abundance of Mosquitoes Biting Nestling Barn Owls (Tyto Alba) in Florida, USA. J Wildl Dis Jul;55(3):597-607
    12. Burkett-Cadena ND, Hoyer I, Blosser E, Reeves L. (2019) Human-powered pop-up resting shelter for sampling cavity-resting mosquitoes. Acta Trop Feb;190:288-292
    13. Diaz A, Coffey LL, Burkett-Cadena N, Day JF. (2018) Reemergence of St. Louis Encephalitis Virus in the Americas. Emerg Infect Dis Dec;24(12)
    14. Sloyer KE, Wisely SM, Burkett-Cadena ND. (2019) Effects of ultraviolet LED versus incandescent bulb and carbon dioxide for sampling abundance and diversity of Culicoides in Florida. J Med Entomol Feb 25;56(2):353-361
    15. Reeves LE, Holderman CJ, Blosser EM, Gillett-Kaufman JL, Kawahara AY, Kaufman PE, Burkett-Cadena ND. (2018) Identification of Uranotaenia sapphirina as a specialist of annelids broadens known mosquito host use patterns. Commun Biol Jul 12;1:92
    16. McGregor BL, Runkel AE 4th, Wisely SM, Burkett-Cadena ND. (2018) Vertical stratification of Culicoides biting midges at a Florida big game preserve. Parasit Vectors Sep 10;11(1):505
    17. Stenn T, Peck KJ, Rocha Pereira G, Burkett-Cadena ND. (2019) Vertebrate Hosts of Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus (Diptera: Culicidae) as Potential Vectors of Zika Virus in Florida. J Med Entomol Jan 8;56(1):10-17
    18. Uysal AK, Martin LB, Burkett-Cadena ND, Barron DG, Shimizu T. (2018) Simulated viral infection in early-life alters brain morphology, activity and behavior in zebra finches (Taeniopygiaguttata). PhysiolBehav Nov 1;196:36-46
    19. Glushakova LG, Alto BW, Kim MS, Wiggins K, Eastmond B, Moussatche P, Burkett-Cadena ND, Benner SA. (2018) Optimization of cationic (Q)-paper for detection of arboviruses in infected mosquitoes. J Virol Methods Nov;261:71-79
    20. McGregor BL, Stenn T, Sayler KA, Blosser EM, Blackburn JK, Wisely SM, Burkett-Cadena ND. (2019) Host use patterns of Culicoides spp. biting midges at a big game preserve in Florida, U.S.A., and implications for the transmission of orbiviruses. Med Vet Entomol Mar;33(1):110-120
    21. Kernbach ME, Hall RJ, Burkett-Cadena ND, Unnasch TR, Martin LB. (2018) Dim light at night: physiological effects and ecological consequences for infectious disease. Integr Comp Biol Nov 1;58(5):995-1007
    22. Erram D, Burkett-Cadena N. (2018) Laboratory studies on the oviposition stimuli of Culicoides stellifer (Diptera: Ceratopogonidae), a suspected vector of Orbiviruses in the United States. Parasit Vectors May 16;11(1):300
    23. Russell JA, Campos B, Stone J, Blosser EM, Burkett-Cadena N, Jacobs JL. (2018) Unbiased Strain-Typing of Arbovirus Directly from Mosquitoes Using Nanopore Sequencing: A Field-forward Biosurveillance Sci Rep Apr 3;8(1):5417
    24. Burkhalter KL, Wiggins K, Burkett-Cadena N, Alto BW. (2018) Laboratory Evaluation of Commercially Available Platforms to Detect West Nile and Zika Viruses From Honey Cards. J Med Entomol May 4;55(3):717-722
    25. Riles MT, Smith JP, Burkett-Cadena N, Connelly CR, Morse GW Jr, Byrd BD. (2017) First Record of Aedes japonicus In Florida. J Am Mosq Control Assoc Dec;33(4):340-344
    26. Hoyer IJ, Blosser EM, Acevedo C, Thompson AC, Reeves LE, Burkett-Cadena ND. (2017) Mammal decline, linked to invasive Burmese python, shifts host use of vector mosquito towards reservoir hosts of a zoonotic disease. Biol Lett Oct;13(10)
    27. Blosser EM, Lord CC, Stenn T, Acevedo C, Hassan HK, Reeves LE, Unnasch TR, Burkett-Cadena ND. (2017) Environmental Drivers of Seasonal Patterns of Host Utilization by Culiseta melanura (Diptera: Culicidae) in Florida. J Med Entomol Sep 1;54(5):1365-1374
    28. Blosser EM, Burkett-Cadena ND. (2017) Oviposition Strategies of Florida Culex (Melanoconion) Mosquitoes. J Med Entomol Jul 1;54(4):812-820
    29. Burkett-Cadena ND, Blosser EM. (2017) Aedeomyia squamipennis (Diptera: Culicidae) in Florida, USA, a New State and Country Record. J Med Entomol May 1;54(3):788-792
    30. Blosser EM, Burkett-Cadena ND. (2017) Culex (Melanoconion) panocossa from peninsular Florida, USA. Acta Trop Mar;167:59-63
    31. Kartzinel MA, Alto BW, Deblasio MW 2nd, Burkett-Cadena ND. (2016) Testing of Visual and Chemical Attractants in Correlation with the Development and Field Evaluation of an Autodissemination Station for the Suppression of Aedes aegypti and Aedes albopictus in Florida. J Am Mosq Control Assoc Sep;32(3):194-202
    32. Blosser EM, Stenn T, Acevedo C, Burkett-Cadena ND. (2016) Host use and seasonality of Culex (Melanoconion) iolambdis (Diptera: Culicidae) from eastern Florida, USA. Acta Trop Dec;164:352-359
    33. Gervasi SS, Burkett-Cadena N, Burgan SC, Schrey AW, Hassan HK, Unnasch TR, Martin LB. (2016) Host stress hormones alter vector feeding preferences, success, and productivity. Proc Biol Sci Aug 17;283(1836)
    34. Burkett-Cadena ND, Gibson J, Lauth M, Stenn T, Acevedo C, Xue RD, McNelly J, Northey E, Hassan HK, Fulcher A, Bingham AM, van Olphen J, van Olphen A, Unnasch TR. (2016) Evaluation of the Honey-Card Technique for Detection of Transmission of Arboviruses in Florida and Comparison With Sentinel Chicken Seroconversion. J Med Entomol Nov;53(6):1449-1457
    35. Bingham AM, Burkett-Cadena ND, Hassan HK, Unnasch TR. (2016) Vector Competence and Capacity of Culex erraticus (Diptera: Culicidae) for Eastern Equine Encephalitis Virus in the Southeastern United States. J Med Entomol Mar;53(2):473-6
    36. Burkett-Cadena ND, Bingham AM, Hunt B, Morse G, Unnasch TR. (2015) Ecology of Culiseta Melanura and Other Mosquitoes (Diptera: Culicidae) from Walton County, FL, During Winter Period 2013-2014. J Med Entomol Sep;52(5):1074-82
    37. Burkett-Cadena ND, Blosser EM, Young RM, Toé LD, Unnasch (2015) Carbon dioxide generated from carbonates and acids for sampling blood-feeding arthropods. Acta Trop Sep;149:254-61
    38. Burkett-Cadena ND, Bingham AM, Unnasch TR. (2014) Sex-biased avian host use by arbovirus vectors. R Soc Open Sci Nov 5;1(3):140262
    39. McGaha TW Jr, Young RM, Burkett-Cadena ND, Iburg JP, Beau JM, Hassan S, Katholi CR, Cupp EW, Baker BJ, Unnasch TR, Noblet (2015) Identification of communal oviposition pheromones from the black fly Simulium vittatum. PLoS One Mar 18;10(3):e0118904
    40. Young RM, Burkett-Cadena ND, McGaha TW Jr, Rodriguez-Perez MA, Toé LD, Adeleke MA, Sanfo M, Soungalo T, Katholi CR, Noblet R, Fadamiro H, Torres-Estrada JL, Salinas-Carmona MC, Baker B, Unnasch TR, Cupp (2015) Identification of human semiochemicals attractive to the major vectors of onchocerciasis. PLoS Negl Trop Dis Jan 8;9(1):e3450
    41. Bingham AM, Burkett-Cadena ND, Hassan HK, McClure CJ, Unnasch TR. (2014) Field investigations of winter transmission of eastern equine encephalitis virus in Florida. Am J Trop Med Hyg Oct;91(4):685-93
    42. Burkett-Cadena ND, Bingham AM, Porterfield C, Unnasch TR. (2014) Innate preference or opportunism: mosquitoes feeding on birds of prey at the Southeastern Raptor Center. J Vector Ecol Jun;39(1):21-31
    43. Toé LD, Koala L, Burkett-Cadena ND, Traoré BM, Sanfo M, Kambiré SR, Cupp EW, Traoré S, Yameogo L, Boakye D, Rodríguez-Pérez MA, Unnasch (2014) Optimization of the Esperanza window trap for the collection of the African onchocerciasis vector Simuliumdamnosumsensulato. Acta Trop Sep;137:39-43
    44. Rodríguez-Pérez MA, Adeleke MA, Burkett-Cadena ND, Garza-Hernández JA, Reyes-Villanueva F, Cupp EW, Toé L, Salinas-Carmona MC, Rodríguez-Ramírez AD, Katholi CR, Unnasch TR. (2013) Development of a novel trap for the collection of black flies of the Simuliumochraceum PLoS One Oct 7;8(10):e76814
    45. Burkett-Cadena N, Graham SP, Giovanetto (2013) Resting environments of some Costa Rican mosquitoes. J Vector Ecol Jun;38(1):12-9
    46. Estep LK, McClure CJ, Vander Kelen P, Burkett-Cadena ND, Sickerman S, Hernandez J, Jinright J, Hunt B, Lusk J, Hoover V, Armstrong K, Stark LM, Hill GE, Unnasch TR. (2013) Risk of exposure to eastern equine encephalomyelitis virus increases with the density of northern cardinals. PLoS One 8(2):e57879
    47. Bingham AM, Graham SP, Burkett-Cadena ND, White GS, Hassan HK, Unnasch TR. (2012) Detection of eastern equine encephalomyelitis virus RNA in North American snakes. Am J Trop Med Hyg Dec;87(6):1140-4
    48. Kelen PT, Downs JA, Burkett-Cadena ND, Ottendorfer CL, Hill K, Sickerman S, Hernandez J, Jinright J, Hunt B, Lusk J, Hoover V, Armstrong K, Unnasch RS, Stark LM, Unnasch TR. (2012) Habitat associations of eastern equine encephalitis transmission in Walton County Florida. J Med Entomol May;49(3):746-56
    49. Estep LK, McClure CJ, Burkett-Cadena ND, Hassan HK, Unnasch TR, Hill GE. (2012) Developing models for the forage ratios of Culiseta melanura and Culex erraticus using species characteristics for avian hosts. J Med Entomol Mar;49(2):378-87
    50. Burkett-Cadena ND, Hassan HK, Eubanks MD, Cupp EW, Unnasch (2012) Winter severity predicts the timing of host shifts in the mosquito Culex erraticus. Biol Lett Aug 23;8(4):567-9
    51. Burkett-Cadena ND, White GS, Eubanks MD, Unnasch TR. (2011) Winter biology of wetland mosquitoes at a focus of eastern equine encephalomyelitis virus transmission in Alabama, USA. J Med Entomol Sep;48(5):967-73
    52. Burkett-Cadena ND. (2011) A wire-frame shelter for collecting resting mosquitoes. J Am Mosq Control Assoc Jun;27(2):153-5
    53. Estep LK, McClure CJ, Burkett-Cadena ND, Hassan HK, Hicks TL, Unnasch TR, Hill GE. (2011) A multi-year study of mosquito feeding patterns on avian hosts in a southeastern focus of eastern equine encephalitis virus. Am J Trop Med Hyg May;84(5):718-26
    54. Gray KM, Burkett-Cadena ND, Eubanks MD, Unnasch TR. (2011) Crepuscular flight activity of Culex erraticus (Diptera: Culicidae). J Med Entomol Mar;48(2):167-72
    55. Burkett-Cadena ND, McClure CJ, Ligon RA, Graham SP, Guyer C, Hill GE, Ditchkoff SS, Eubanks MD, Hassan HK, Unnasch TR. (2011) Host reproductive phenology drives seasonal patterns of host use in mosquitoes. PLoS One Mar 7;6(3):e17681
    56. Oliveira A, Katholi CR, Burkett-Cadena N, Hassan HK, Kristensen S, Unnasch TR. (2011) Temporal analysis of feeding patterns of Culex erraticus in central Alabama. Vector Borne Zoonotic Dis Apr;11(4):413-21
    57. Estep LK, Burkett-Cadena ND, Hill GE, Unnasch RS, Unnasch TR. (2010) Estimation of dispersal distances of Culex erraticus in a focus of eastern equine encephalitis virus in the southeastern United States. J Med Entomol Nov;47(6):977-86
    58. Burkett-Cadena ND, Ligon RA, Liu M, Hassan HK, Hill GE, Eubanks MD, Unnasch TR. (2010) Vector-host interactions in avian nests: do mosquitoes prefer nestlings over adults? Am J Trop Med Hyg Aug;83(2):395-9
    59. Jacob BG, Burkett-Cadena ND, Luvall JC, Parcak SH, McClure CJ, Estep LK, Hill GE, Cupp EW, Novak RJ, Unnasch TR. (2010) Developing GIS-based eastern equine encephalitis vector-host models in Tuskegee, Alabama. Int J Health Geogr Feb 24;9:12
    60. Graham SP, Hassan HK, Burkett-Cadena ND, Guyer C, Unnasch TR. (2009) Nestedness of ectoparasite-vertebrate host networks. PLoS One Nov 18;4(11):e7873
    61. Ligon RA, Burkett-Cadena ND, Liu M, Hill GE, Hassan HK, Unnasch TR. (2009) Assessing mosquito feeding patterns on nestling and brooding adult birds using microsatellite markers. Am J Trop Med Hyg Sep;81(3):534-7
    62. Gray KM, Burkett-Cadena ND, Eubanks MD. (2008) Distribution expansion of Culex coronator in Alabama. J Am Mosq Control Assoc Dec;24(4):585-7
    63. Burkett-Cadena ND, Graham SP, Hassan HK, Guyer C, Eubanks MD, Katholi CR, Unnasch (2008) Blood feeding patterns of potential arbovirus vectors of the genus culex targeting ectothermic hosts. Am J Trop Med Hyg Nov;79(5):809-15
    64. Burkett-Cadena ND, Mullen GR. (2008) Comparison of infusions of commercially available garden products for collection of container-breeding mosquitoes. J Am Mosq Control Assoc Jun;24(2):236-43
    65. Burkett-Cadena ND, Eubanks MD, Unnasch TR. (2008) Preference of female mosquitoes for natural and artificial resting sites. J Am Mosq Control Assoc Jun;24(2):228-35
    66. Burkett-Cadena ND, Mullen GR. (2007) Field comparison of Bermuda-hay infusion to infusions of emergent aquatic vegetation for collecting female mosquitoes. J Am Mosq Control Assoc Jun;23(2):117-23

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    Barry Alto

    Associate Professor

    Mosquito Ecology - Disdease Transmission
    bwalto@ufl.edu
    Appointments, Awards, and Professional Service:
    • 2016-present, Editorial Board, Entomological Society of America (Environmental Entomology).
    • 2015-present, Board of Directors (Member-at-Large), Florida Mosquito Control Association.
    • 2014, Richard Jones Outstanding New Faculty Research Award, Institute of Food and Agricultural Sciences, University of Florida.
    • 2011-2014, Editorial Board (served as chair in 2014), Entomological Society of America (Journal of Medical Entomology).
    • 2011-2014, Faculty Assembly representative, Institute of Food and Agricultural Sciences, University of Florida.
    • 2014-present, Institute of Food and Agricultural Sciences Faculty Research Advisory Group, University of Florida.