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Florida Medical Entomology Laboratory

Florida Medical Entomology Laboratory

Dr. Yoosook Lee

Yoosook Lee

Yoosook Lee

Assistant Professor

Molecular Ecology, Population Genomics, Bioinformatics
yoosook.lee@ufl.edu

 

I study natural populations of arthropod vectors. Population Biology, Ecology and Evolution is particularly critical for disease vectors because, even in a single town, populations with limited gene flow show phenotypic differences important for public health and pest management. I am particularly interested in population divergence, dispersal, genetic variations associated with epidemiologically important phenotypes such as insecticide resistance and pathogen resistance. These aspects are critical in translating basic research of ecology and evolution to applied vector control efforts including the use of genetically altered mosquitoes. Dispersal has particular importance to innovative pest management strategies such as ‘Auto-Dissemination’ or genetically engineered mosquitoes.

My work involves next generation sequencing and big data analysis, most often combined with more traditional marker-based genotyping of large numbers of samples from natural populations for validation and generalization. Using a combination of genomics and bioinformatics tools, I develop multi-detection assays for species and hybrid identification, pathogen detection, chromosome inversion genotyping, and blood source detection for various insect species groups. My current research focus centers around arbovirus vectors such as Aedes aegypti and Aedes albopictus worldwide, and malaria vectors such as Anopheles funestus complex in southern Africa and Anopheles darlingi in Brazil.

I have extensive research mentoring experience for undergraduate students, graduate students and postdoctoral researchers. Many of my trainees including international scholars have published peer-reviewed articles with me. I am particularly proud of the fact that majority of undergraduate students have peer-review publications with me before they graduate. I welcome enthusiastic students interested in integrative approach in solving complex problem of vector-borne diseases.

Yoosook Lee

Yoosook Lee

Assistant Professor

Molecular Ecology, Population Genomics, Bioinformatics
yoosook.lee@ufl.edu

 

  • PostDoctoral Researcher, University of California Davis, Population Genetics and Bioinformatics 2006-2010
  • Ph.D., Biology, University of California Los Angeles, 2006
  • B.S., Life Science, Pohang Institute of Science and Technology (POSTECH) 2000
Yoosook Lee

Yoosook Lee

Assistant Professor

Molecular Ecology, Population Genomics, Bioinformatics
yoosook.lee@ufl.edu

 

Publications

  1. Peer-reviewed journals
  2. Extension Publications
  3. Other research publications
  4. Bookchapters
  5. Abstracts

 

Journals

87

2024

Collier TC, Lee Y, Mathias DK, Del Amo VL. CRISPR-Cas9 and Cas12a Target Site Richness Reflects Genomic diversity in natural populations of Anopheles gambiae and Aedes aegypti mosquitoes. BMC Genomics. 2024. 25: 700. https://doi.org/10.1186/s12864-024-10597-4 

86

2024

Telmaderrehei T, Romero-Weaver AL, Lee Y†, Minteer C†. First complete mitogenome sequence of a biological control agent insect, Pseudophilothrips ichini (Hood). Florida Entomol. 2024. 107(1):20240014. https://doi.org/10.1515/flaent-2024-0014

85

2024

Seok S, Mogi M, Lee Y. Resolving confusion in the native distribution of Aedes (Hulecoeteomyia) koreicus (Diptera: Culicidae). J Med Entomol. 2024. tjae078, https://doi.org/10.1093/jme/tjae078 

84
2024

Kosinski KJ, Romero-Weaver A, Nguyen VT, Mathias DK, Buckner EA, Lee Y. A new multiplex SNP genotyping assay to simultaneously screen eight voltage-gated sodium channel mutations of Aedes aegypti. 2023. J Florida Mosq Control Assoc. 2024. 71(1): 41-49.  DOI: https://doi.org/10.32473/jfmca.71.1.135292

83
2023

Ditter RE, Campos M, Crepeau MW, Pinto J, Toilibou A, Amina Y, Tantely LM, Girod R, Lee Y, Cornel AJ, Lanzaro GC. Anopheles gambiae on remote islands in the Indian Ocean: origins and prospects for malaria elimination by genetic modification of extant populations. Sci Rep. 2023. 13(1):20830. doi: 10.1038/s41598-023-44501-z. PMCID: PMC10682471.

82
2023

Seok S, Kim Z, Nguyen VT, Lee Y. The potential invasion into North America and Europe by non-native mosquito Aedes koreicus (Diptera: Culicidae). J Med Entomol. 2023. 60(6):1305-1313. https://doi.org/10.1093/jme/tjad116

81
2023

Soudi S, Crepeau M, Collier TC, Lee Y, Cornel AJ, Lanzaro GC. Genomic signatures of local adaptation in recent invasive Aedes aegypti populations in California. BMC Genomics. 2023. 24(1):311. doi: 10.1186/s12864-023-09402-5. PMCID: PMC10257851.

80
2023

Nguyen VT, Collier TC, Seok S, Wang X, Mburu MM, Simubali L, Gebhardt ME, Norris DE, Lee Y. The first genome sequence of Anopheles squamous from Macha, Zambia.  F1000Research. 12:330 (https://doi.org/10.12688/f1000research.130734.1)

79 2023

Nguyen VT, Romero-Weaver AL, Wang X, Tavares Y, Bauer A, McDowell RC, Dorsainvil C, Eason MD, Malcolm AN, Raz CD, Byrd BD, Riegel C, Clark M, Ber J, Harrison R, Evans C, Zohdy S, Allen B, Campbell LP, Killingsworth D, Grey EW, Riles M, Lee Y*, Giordano BV. [*Lee Y – Corresponding author] Survey of mosquito surveillance and control capacity in the southern United States reveals training gaps and resource needs. J Am Mosquito Cntrl Assoc. ** In Press **

78 2023

Seok S, Raz CD, Miller JH, Malcolm AN, Eason MD, Romero-Weaver AL, Giordano BV, Jacobsen CM, Wang X, Akbari OS, Raban R, Mathias DK, Caragata EP, Vorsino AE, Chiu JC, Lee Y. Arboviral disease outbreaks, Aedes mosquitoes, and vector control efforts in the Pacific islands. Frontiers Trop Dis. 4:1035273. https://doi.org/10.3389/fitd.2023.1035273

77 2023

Brisco KK, Jacobsen CM, Seok S, Wang X, Lee Y*, Akbari OS, Cornel AJ. Field Evaluation of In2Care Mosquito Traps to Control Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in Hawai'i Island. J Med Entomol. 2023. 60(2): 364-372. doi: 10.1093/jme/tjad005. [*Lee Y – Corresponding author]

76 2023

Seok S, Jacobsen CM, Romero-Weaver AL, Wang Xiaodi, Nguyen VT, Collier TC, Riles MT, Akbari OS, Lee Y. Complete mitogenome sequence of Aedes (Hulecoeteomyia) japonicus japonicus from Hawai’i Island. Mitochondrial DNA Part B Resourc. 2023. 8(1): 64-68. https://doi.org/10.1080/23802359.2022.2161328. PMCID: PMC9848326

75 2023

Campos M, Patel N, Marshall C, Gripkey H, Ditter RE, Crepeau MW, Toilibou A, Amina Y, Cornel AJ, Lee Y, Lanzaro GC. Population genetics of Anopheles pretoriensis in Grande Comore Island. Insects. 2023, 14(1), 14; https://doi.org/10.3390/insects14010014. PMCID: PMC9866569

74 2022

Niang A, Maïga H, Sawadogo SP, Konaté L, Faye O, Lee Y, Dabiré RK, Diabaté A, Tripet F. Perfect association between spatial swarm segregation and the X-chromosome speciation island in hybridizing Anopheles coluzzii and Anopheles gambiae populations. Sci Rep. 2022 Jun 24;12(1):10800. doi: 10.1038/s41598-022-14865-9. PMCID: PMC9232630.

73

2022

Kosinski KJ, Lee Y, Romero-Weaver AL, Chen T-Y, Collier TC, Wang X, Mathias DK, Buckner EA. Two novel SNPs in voltage-gated sodium channel gene identified in Aedes aegypti mosquitoes from Florida. Journal of Florida Mosquito Control Associations. 2022. 69(1):21-28.  DOI: https://doi.org/10.32473/jfmca.v69i1.130622

72

2022

Rashid I, Campos M, Collier T, Crepeau M, Weakley A, Gripkey H, Lee Y, Schmidt H, Lanzaro GC. Spontaneous mutation rate estimates for the principal malaria vectors Anopheles coluzzii and Anopheles stephensi. Scientific Reports.  2022. 22:226. https://doi.org/10.1038/s41598-021-03943-z. PMCID: PMC8742016

71

2021

Jones CM, Ciubotariu II, Muleba M, Lupiya J, Mbewe D, Simubali L, Mudenda T, Gebhardt M, Carpi G, Malcolm AN, Kosinski KJ, Romero-Weaver AL, Stevenson JC, Lee Y, Norris DE. Multiple novel clades of anopheline mosquitoes caught outdoors in northern Zambia. Frontiers Trop Dis. 2021. 2:780664. https://doi.org/10.3389/fitd.2021.780664. PMCID: PMC9384971

70

2021

Lewald K, Abrieux A, Wilson D, Lee Y, Conner W, Andreazza F, Beers E, Burrack H, Daane K, Diepenbrock L, Drummond F, Fanning P, Gaffney M, Hesler S, Ioriatti C, Isaacs R, Little B, Loeb G, Miller B, Nava D, Rendon D, Sial A, Da Silva C, Stockton D, Van Timmeren S, Wallingford A, Walton V, Wang X, Zhao B, Zalom F, Chiu J. Population genomics of Drosophila suzukii reveal longitudinal population structure and signals of migrations in and out of the continental United States. G3 (Bethesda). 2021. jkab343. https://doi.org/10.1093/g3journal/jkab343. PMCID: PMC8664444

69

2021

Chen T-Y, Lee Y, Wang X, Mathias D, Caragata EP, Smartt CT. Profiling transcriptional response of Dengue-2 virus infection in midgut tissue of Aedes aegypti. Frontiers in Tropical Diseases. Front Trop Dis. 2021. 2:17. https://doi.org/10.3389/fitd.2021.708817

68

2021

Kondapaneni R, Malcolm AN, Vazquez BM, Zeng E, Chen T, Kosinski KJ, Romero-Weaver AL, Giordano BV, Allen B, Riles MT, Killingsworth D, Campbell LP, Caragata EP, Lee Y. Mosquito control priorities in Florida – Survey results from Florida Mosquito Control Districts. Pathogens. 10(8), 947; https://doi.org/10.3390/pathogens10080947. PMCID: PMC8401384. (Part of Special Issue "Mosquito-Borne Diseases: Novel Control Strategies")

67

2021

Kelly ET, Mack LK, Campos M, Grippin C, Chen, T, Romero-Weaver AL, Kosinski KJ, Brisco KK, Collier TC, Buckner EA, Campbell LP, Cornel AJ, Lanzaro GC, Rosario-Cruz R, Smith K, Attardo GM, Lee Y. Evidence of local extinction and reintroduction of Aedes aegypti in Exeter, California. Frontiers in Tropical Diseases. 2021. 2:8. https://doi.org/10.3389/fitd.2021.703873 (Part of Research Topic “Biology, Systemics, Taxonomy, and Evolution of Insect Vectors” and e-Boook edited by Oliveira et al. DOI: https://doi.org/10.3389/978-2-88974-741-2)

66

2021

Campos M, Hanemaaijer M, Gripkey H, Collier TC, Lee Y, Cornel AJ, Pinto J, Rompão H, Lanzaro GC. The origin of island populations of the African malaria mosquito, Anopheles coluzzii. Communications Biol. 2021. 4:630. https://www.nature.com/articles/s42003-021-02168-0. PMCID: PMC8155153

65

2021

Chen T, Vorsino AE, Kosinski KJ, Romero-Weaver AL, Buckner EA, Chiu JC, Lee Y. A magnetic-beads-based mosquito DNA extraction protocol for high throughput sequencing. J. Vis. Exp. 2021. 170: e62354, https://dx.doi.org/10.3791/62354

64

2021

Mack LK, Kelly ET, Lee Y, Brisco KK, Shen KV, Zahid A, Van Schoor T, Cornel AJ, Attardo GM. Frequency of sodium channel genotypes and association with pyrethrum knockdown time in populations of Californian Aedes aegypti. Parasit Vectors. 2021. 14(1):141. doi: 10.1186/s13071-021-04627-3. PMCID: PMC7936502

63

2020

Lee Y, Souvannaseng L, Collier TC, Main BJ, Norris LC, Fofana A, Traore SF, Cornel AJ, Luckhart S, Lanzaro GC. ­­Evidence for divergent selection on immune genes between the African malaria vectors, Anopheles coluzzii and A. gambiae. Insects. 11(12): 893; https://doi.org/10.3390/insects11120893. PMCID: PMC7767042

62

2020

Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen C, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, Evans SW, Friedman RM, Gantz VM, Gould F, Hartley S, Heitman E, Hemingway J, Kanuka H, Kuzma J, Lavery JV, Lee Y, Lorenzen M, Lunshof JE, Marshall JM, Messer PW, Montell C, Oye KA, Palmer MJ, Papathanos PA, Paradkar PN, Piaggio AJ, Rasgon JL, Rašić G, Rudenko L, Saah JR, Scott MJ, Sutton JT, Vorsino A, Akbari OS. Core commitments for field trials of gene drive organisms. Science. 370(6523): 1417-1419. DOI: 10.1126/science.abd1908

61

2020

Campos M, Crepeau M, Lee Y, Gripkey H, Rompão H, Cornel AJ, Pinto J, Lanzaro GC. Complete mitogenome sequence of Anopheles coustani from São Tomé island. Mitochondrial DNA Part B Resourc. 5:3, 3394-3396, https://doi.org/10.1080/23802359.2020.1823273. PMCID: PMC7782027

60

2020

Kreppel KS, Viana M, Main BJ, Johnson PCD, Govella NJ, Lee Y, Maliti D, Meza FC, Lanzaro GC, Ferguson HM. Emergence of behavioural avoidance strategies of malaria vectors in areas of high LLIN coverage in Tanzania. Sci Rep. 2020. 10(1):14527. doi: 10.1038/s41598-020-71187-4. PMCID: PMC7471940.

59

2020

Carballar-Lejarazú R, Ogaugwu C, Tushar T, Kelsey A, Pham TB, Murphy J, Schmidt H, Lee Y, Lanzaro G, James AA. Next-generation gene drive for population modification of the malaria vector mosquito, Anopheles gambiae. PNAS. 117(37):22805-22814. https://doi.org/10.1073/pnas.2010214117. PMCID: PMC7502704

58

2020

Braack L, Bornman R, Kruger T, Dahan Y, Gilbert A, Kaiser M, Oliver S, Cornel AJ, Lee Y, Norris DE, Coetzee M, Brooke B, De Jager C. Malaria vectors and vector surveillance in Limpopo Province (South Africa) 1927 to 2018. Int. J. Environ. Res. Public Health 17(11), 4125; https://doi.org/10.3390/ijerph17114125. PMCID: PMC7313001

57

2020

Schmidt H, Collier TC, Hanemaaijer MJ, Houston PD, Lee Y, Lanzaro GC. Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes. Nat Commun. 11(1):1425. doi: 10.1038/s41467-020-15204-0. PMCID:PMC7080748.

56

2020

Cornel AJ, Bargielowski IE, Collier TC, Weakley AM, Blosser EM, Lanzaro GC, Hulshof K, Braks MAH, Lee Y. Complete mitogenome sequences of Aedes (Howardina) busckii and Aedes (Ochlerotatus) taeniorhynchus from the Caribbean Island of Saba. Mitochondrial DNA Part B Resourc. 5(2), 1163-1164, DOI:10.1080/23802359.2020.1730720

55

2020

Li M, Yang T, Kandul N, Bui M, Gamez S, Raban R, Bennett J, Sanchez C. HM, Lanzaro GC, Schmidt H, Lee Y, Marshall JM, Akbari OS. Development of a Confinable Gene-Drive System in the Human Disease Vector, Aedes aegypti. eLife. 9:e51701. DOI: 10.7554/eLife.51701. PMCID: PMC6974361.

54

2019

Schmidt H, Lee Y, Collier TC, Hanemaaijer MJ, Kirstein OD, Ouledi A, Muleba M, Norris DE, Slatkin M, Cornel AJ, Lanzaro GC. Transcontinental dispersal of Anopheles gambiae occurred from West African origin via serial founder events. Commun Biol. 2:473. doi: 10.1038/s42003-019-0717-7. PMCID: PMC6923408.

53

2019

Martinez-Villegas L, Assiss-Geraldo J, Koerich LB, Collier TC, Lee Y, Main BJ, Lanzaro GC, Pimenta PFP. Characterization of the complete mitogenome of Anopheles aquasalis, and phylogenetic divergences among Anopheles from diverse geographic zones. PLoS One 14(9): e0219523. https://doi.org/10.1371/journal.pone.0219523. PMCID:PMC6720026

52

2019

Guagliardo SAJ, Lee Y, Pierce A, Wong J, Chu YY, Morrison AC, Astete H, Brosi B, Vazquez-Prokopec G, Scott TW, Kitron U, Stoddard ST. The genetic structure of Aedes aegypti populations is driven by boat traffic in the Peruvian Amazon. PLoS Neg Trop Dis. 13(9):e0007552. http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0007552. PMCID:PMC6750575

51

2019

Torres MG, Weakley AM, Hibbert JD, Kirstein OD, Lanzaro GC, Lee Y. Ethanol as potential mosquito sample storage medium for RNA preservation. F1000Research. 8:1431 DOI:https://doi.org/10.12688/f1000research.20162.1. PMCID:PMC6713064

50

2019

Tabuloc CA, Lewald KM, Conner WR, Lee Y, Lee EK, Cain AB, Godfrey KE, Pujol JA, Agustí N, Zalom FG, Chiu JC. Sequencing of Tuta absoluta genome to facilitate the development of SNP genotyping assays for species identification. J Pest Sci. 92:1397-1407. doi: https://doi.org/10.1007/s10340-019-01116-6

49

2019

Hanemaaijer MJ, Higgins H, Eralp I, Yamasaki Y, Becker N, Kirstein OD, Lanzaro GC, Lee Y. Introgression between Anopheles gambiae and Anopheles coluzzii in Burkina Faso and its associations with kdr resistance and Plasmodium infection. Malar J. 18:127. https://doi.org/10.1186/s12936-019-2759-1. PMCID:PMC6458625

48

2019

(v1 in 2018)

Hanemaaijer MJ, Houston P, Collier TC, Norris LC, Fofana A, Lanzaro GC, Cornel AJ, Lee Y. Mitochondrial genomes of Anopheles arabiensis, An. gambiae and An. coluzzii show no clear species division. F1000 Research. 7:347 DOI: 10.12688/f1000research.13807.2. PMCID: PMC6489993

47

2019

Lee Y, Schmidt H, Collier TC, Conner WR, Hanemaaijer MJ, Slatkin M, Marshall JM, Chiu JC, Smartt CT, Lanzaro GC, Mulligan FS, Cornel AJ. Genome-wide divergence among invasive populations of Aedes aegypti in California. BMC Genomics. 20(1):204. doi: https://doi.org/10.1186/s12864-019-5586-4. PMCID:PMC6417271

46

2018

Hanemaaijer MJ, Collier TC, Chang A, Shott CC, Houston PD, Schmidt H, Main BJ, Cornel AJ, Lee Y, Lanzaro GC. The fate of genes that cross species boundaries after a major hybridization event in a natural mosquito population. Mol Ecol. 27(24):4978-4990. doi: https://doi.org/10.1111/mec.14947.

45

2018

Schmidt H, Hanemaaijer MJ, Cornel AJ, Lanzaro GC, Braack L, Lee Y. Complete mitogenome sequence of Aedes (Stegomyia) aegypti derived from field isolates from California and South Africa. Mitochondrial DNA B Resour. 3(2): 994-995, https://doi.org/10.1080/23802359.2018.1495117. PMCID: PMC7800648

44

2018

Jones CM, Lee Y, Kitchen A, Collier T, Pringle JC, Muleba M, Irish S, Stevenson JC, Coetzee M, Cornel AJ, Norris DE, Carpi G. Complete Anopheles funestus mitogenomes reveal an ancient history of mitochondrial lineages and their distribution in southern and central Africa. Sci Rep. 8:9054. https://doi.org/10.1038/s41598-018-27092-y. PMCID:PMC5997999

43

2018

Loiseau C, Melo M, Lee Y, Pereira H, Hanemaaijer M, Lanzaro G, Cornel AJ. High endemism of mosquitoes on São Tomé and Principe Islands: evaluating the general dynamic model in a worldwide island comparison. Insect Conservation and Diversity. 12(1):1651-1673 https://doi.org/10.1111/icad.12308

42

2018

Cornel AJ, Lee Y, Almeida APG, Johnson T, Mouatcho J, Venter M, de Jager C, Braack L. Mosquito community composition in South Africa and some neighboring countries. Parasit Vectors. 11:331. https://doi.org/10.1186/s13071-018-2824-6. PMCID:PMC5984792

41

2016

Main BJ, Lee Y, Kreppel KS, Ferguson HM, Collier TC, Kihonda A, Govella NJ, Kang EY, Nieman CC, Weakley AM, Eskin E, Cornel AJ, Lanzaro GC. The Genetic Basis of host preference and indoor resting behavior in the major African malaria vector, An. arabiensis. PLoS Genetics. 12(9): e1006303. doi:10.1371/journal.pgen.1006303. PMCID:PMC5025075.

40

2016

Cornel AJ, Brisco KK, Tadei WP, Secundino NF, Galardo AKR, Medeiros JF, Pessoa FAC, Rios-Velasquez CM, Lee Y, Pimenta PFP, Lanzaro GC. Anopheles darlingi polytene chromosomes: revised maps including newly described inversion and evidence for population structure in Manaus. Memorias. 2016. 111(5):335-346. PMCID: PMC4878303.

39

2016

Brisco KK, Cornel AJ, Lee Y, Mouatcho J, Braack L. Comparing efficacy of a sweep net and a dip method for collection of mosquito larvae in large bodies of water in South Africa. F1000Res. 5:713. (doi: 10.12688/f1000research.8351.1) *** INDEXED ***. PMCID:PMC5390499

38

2016

Maliti DV, Marsden CD, Main BJ, Govella NJ, Yamasaki Y, Collier TC, Kreppel K, Chiu JC, Lanzaro GC, Ferguson HM, Lee Y. Investigating associations between biting time in the malaria vector Anopheles arabiensis Patton and single nucleotide polymorphisms in circadian clock genes: support for sub-structure among An. arabiensis in the Kilombero valley of Tanzania. Parasit Vectors. 2016. 9(1):109. Doi: 10.1186/s13071-016-1394-8. PMCID: PMC4769569.

37

2016

Cornel AJ, Holeman J, Nieman CC, Lee Y*, Smith C, Amorino M, Brisco K, Barrera R, Lanzaro GC, Mulligan III FS. Surveillance, insecticide resistance and control of an invasive Aedes aegypti (Diptera: Culicidae) population in California. F1000Res. 5:194. doi: 10.12688/f1000research.8107.3. [*Lee Y – Corresponding author]. PMCID: PMC4857756.

36

2015

Nieman CC, Yamasaki Y, Collier TC, Lee Y. A DNA extraction protocol for improved DNA yield from individual mosquitoes. F1000research, 4: 1314. https://doi.org/10.12688/f1000research.7413.1 PMCID: PMC4743141.

35

2015

Main BJ, Lee Y, Norris LC, Collier TC, Fofana A, Cornel AJ, Lanzaro GC. Complex Genome Evolution in A. coluzzii Associated with Increased Insecticide Usage in Mali. Mol Ecol. 24(20): 5145-5157. PMCID: PMC4615556.

34

2015

Lanzaro GC, Collier TC, Lee Y. Defining genetic, taxonomic and geographic boundaries among species of the Psorophora confinnis (Diptera:Culicidae) complex in the Americas. J Med Entomol. 52(5):907-17., DOI: http://dx.doi.org/10.1093/jme/tjv084

33

2015

Norris LC, Main BJ, Lee Y, Collier T, Fofana A, Cornel AJ, Lanzaro GC. Adaptive introgression in an African malaria mosquito coincident with the increased usage of insecticide-treated bed nets. PNAS. 112(3):815-820. PMCID: PMC4311837.

32

2015

Ng'habi KR, Lee Y, Knols BG, Mwasheshi D, Lanzaro GC, Ferguson HM. Colonization of malaria vectors under semi-field conditions as a strategy for maintaining genetic and phenotypic similarity with wild populations. Malar J. 2015. 14:10. doi: 10.1186/s12936-014-0523-0. PMCID: PMC4340333.

31

2015

Lee Y, Weakley AM, Nieman CC, Malvick J, Lanzaro GC. A multi-detection assay for malaria transmitting mosquitoes. J Vis Exp. (96):e52385. doi:10.3791/52385. http://www.jove.com/video/52385/a-multi-detection-assay-for-malaria-transmitting-mosquitoes. PMCID:PMC4401152

30

2015

Lee Y, Olson N, Yamasaki Y, Chang A, Marsden CD, Lanzaro GC, Cornel AJ. Absence of KDR resistance alleles in the Union of the Comoros, East Africa. F1000research. 2015. 4:146. PMCID: PMC4544377.

29

2014

Sanford MR, Cornel AJ, Nieman CC, Dinis J, Marsden CD, Weakley AM, Han S, Rodrigues A, Lanzaro G, Lee Y. Plasmodium falciparum infection rates for some Anopheles spp. from Guinea­-Bissau, West Africa. F1000Research, 3:243. PMCID: PMC4215749.

28

2014

Lee Y, Marsden CD, Nieman C, Lanzaro GC. A new multiplex SNP genotyping assay for detecting hybridization and introgression between the M and S molecular forms of Anopheles gambiae. Mol Ecol Resourc, 14(2): 297-305. PMCID: PMC3947471.

27

2014

Marsden CD, Lee Y, Kreppel K, Weakley A, Cornel A, Ferguson HM, Eskin E, Lanzaro GC. Diversity, differentiation and linkage disequilibrium: prospects for association mapping in the malaria vector, Anopheles arabiensis. G3, 4(1): 121-31. PMCID: PMC3887528.

26

2013

Lee Y, Marsden CD, Norris LC, Collier TC, Main BJ, Fofana A, Cornel AJ, Lanzaro GC. Spatio-temporal dynamics of gene flow and hybrid fitness between the M and S forms of the malaria mosquito, Anopheles gambiae. Proc Natl Acad Sci U S A. 110(49):19854-9. PMCID: PMC3856788.

25

2013

Sanford MR, Ramsay S, Cornel AJ, Marsden CD, Norris LC, Patchoke S, Fondjo E, Lanzaro GC, Lee Y. A preliminary investigation of the relationship between water quality and Anopheles gambiae larval habitats in Western Cameroon. Malar J. 12:225. PMCID: PMC3704728.

24

2013

Lee Y, Collier TC, Sanford MR, Marsden CD, Fofana A, Cornel AJ, Lanzaro GC. Chromosome Inversions, Genomic Differentiation and Speciation in the African Malaria Mosquito Anopheles gambiae. PLoS One, 8(3): e57887. PMCID: PMC3603965.

23

2013

Marsden CD, Cornel A, Lee Y, Sanford MR, Norris LC, Goodell PB, Nieman CC, Han S, Rodrigues A, Denis J, Ouledi A, Lanzaro GC. An analysis of two island groups as potential sites for trials of transgenic mosquitoes for malaria control. Evol Appl, 6(4): 706-20. PMCID: PMC3684749.

22

2012

Cornel A, Lee Y, Fryxell RT, Seifert S, Nieman C, Lanzaro G. Culex pipiense sensu lato in California: a complex within a complex? J Am Mos Control Assoc, 28(4s): 113-121. DOI: 10.2987/8756-971X-28.4s.113

21

2012

Trout Fryxell RT, Seifert SN, Lee Y, Sacko A, Lanzaro G, Cornel A. The kdr mutation and knockdown time in Anopheles gambiae (Diptera: Culicidae) collected from Mali evaluated through a bottle bioassay and a novel insecticide treated net (ITN) bioassay.  J Am Mosq Control Assoc. 28(2):119-22. DOI: 10.2987/11-6216R.1

20

2012

Trout Fryxell RT, Nieman CC, Fofana A, Lee Y, Traore SF, Cornel AJ, Luckhart S, Lanzaro GC. Differential Plasmodium falciparum infection of Anopheles gambiae s.s. molecular and chromosomal forms in Mali. Malar J. 11:133. PMCID:PMC3441388.

19

2012

Demirci B, Lee Y, Lanzaro GC, Alten B. Altitudinal genetic and morphometric variation among populations of Culex theileri Theobald (Diptera: Culicidae) from northeastern Turkey. J Vector Ecol, 37(1): 197-209. DOI: 10.1111/j.1948-7134.2012.00217.x.

18

2012

Demirci B, Lee Y, Lanzaro GC, Alten B. Identification and characterization of single nucleotide polymorphisms (SNPs) in Culex theileri Theobald (Diptera: Culicidae). J Med Entomol, 49(3): 581-588. DOI: 10.1603/me11139.

17

2012

Lee Y, Seifert SN, Fornadel CM, Norris DE, Lanzaro GC. Single nucleotide polymorphisms for high-throughput genotyping of Anopheles arabiensis in East and Southern Africa. J Med Entomol, 49(2): 307-315. PMCID: PMC4089035.

16

2012

Lee Y, Seifert SN, Nieman CC, McAbee RD, Goodell P, Fryxell RT, Lanzaro GC, Cornel AJ. High degree of single nucleotide polymorphisms in California Culex pipiens (Diptera;Culicidae) sensu lato. J Med Entomol. 2012 Mar;49(2):299-306. PMCID: PMC3553656.

15

2012

Wong J, Chu YY, Stoddard ST, Lee Y, Morrison AC, Scott TW. Microsatellite-Based Parentage Analysis of Aedes aegypti (Diptera: Culicidae) Using Non-Lethal DNA Sampling. J Med Entomol, 49(1): 85-93. PMCID: PMC3312012.

14

2011

Sanford MR, Demirci B, Marsden CD, Lee Y, Cornel AJ, Lanzaro GC. Morphological Differentiation may Mediate Mate-Choice between Incipient Species of Anopheles gambiae s.s. PLoS One, 6(11): e27920. PMCID: PMC3221689.

13

2011

Marsden CD, Lee Y, Neiman C, Sanford MR, Dinis J, Marins C, Rodrigues AR, Cornel AJ, Lanzaro GC. Asymmetric introgression between the M and S molecular forms of the malaria vector, Anopheles gambiae, maintains divergence despite extensive hybridisation. Mol Ecol, 20(23): 4983-4994. PMCID: PMC3222736.

12

2011

Ng'habi KR, Knols BGJ, Lee Y, Ferguson HM, Lanzaro GC. Population genetic structure of Anopheles arabiensis and Anopheles gambiae in a malaria endemic region of southern Tanzania. Malar J. 10: 289. PMCID:PMC3195206.

11

2010

Horton AA, Lee Y, Coulibaly CA, Rashbrook VK, Cornel AJ, Lanzaro GC, Luckhart S. Identification of three single nucleotide polymorphisms in Anopheles gambiae immune signaling genes that are associated with natural Plasmodium falciparum infection. Malar J, 9: 160. PMCID: PMC2896950.

10

2009

Lee Y, Collier TC, Taylor CE, Olfati-Saber R. Simplicity from complexity: Emergence of cohesion in the evolutionary dynamics of grammar networks. Evol Ecol Res, 11(5): 433-445. [PDF]

9

2009

Lee Y, Cornel AJ, Meneses CR, Fofana A, Andrianarivo AG, McAbee RD, Fondjo E, Traoré SF, Lanzaro GC. Ecological and genetic relationships of the Forest-M form among chromosomal and molecular forms of the malaria vector Anopheles gambiae sensu stricto. Malar J, 8: 75. PMCID:PMC2680901

8

2009

Lee Y, Meneses CR, Fofana A, Lanzaro GC. Desiccation resistance among subpopulations of Anopheles gambiae s.s. from Selinkenyi, Mali. J Med Entomol, 46(2): 316-20. DOI: 10.1603/033.046.0216

7

2008

Jung KH, Lee J, Dardick C, Seo YS, Cao P, Canlas P, Phetsom J, Xu X, Ouyang S, An K, Cho YJ, Lee GC, Lee Y, An G, Ronald PC. Identification and functional analysis of light-responsive unique genes and gene family members in rice. PLoS Genet, 4(8): e1000164. PMCID: PMC2515340.

6

2008

Reimer L, Fondjo E, Patchoké S, Diallo B, Lee Y, Ng A, Ndjemai HM, Atangana J, Traore SF, Lanzaro G, Cornel AJ. Relationship between kdr mutation and resistance to pyrethroid and DDT insecticides in natural populations of Anopheles gambiae. J Med Entomol, 45(2): 260-6. DOI:https://doi.org/10.1093/jmedent/45.2.260

5

2007

Slotman MA, Tripet F, Cornel AJ, Meneses CR, Lee Y, Reimer LJ, Thiemann TC, Fondjo E, Fofana A, Traoré SF, Lanzaro GC. Evidence for subdivision within the M molecular form of Anopheles gambiae. Mol Ecol, 16(3): 639-49. DOI: 10.1111/j.1365-294X.2006.03172.x

4

2005

Lee Y, Collier TC, Taylor CE, Stabler EP. The role of population structure in language evolution. Proceedings of the 10th International Symposium on Artificial Life and Robotics. [PDF]

3

2005

Lee Y, Collier TC, Taylor CE, Stabler EP. Grammar Structure and the Dynamics of Language Evolution. Advances in Artificial Life: 8th European Conference, ECAL 2005, 624-633. [link]

2

2004

Lee Y, Riggle J, Collier TC, Stabler EP, Taylor CE. Adaptive Communication among Collaborative Agents: Preliminary Results with Symbol Grounding. Artificial Life and Robotics, 8(2): 127-132. DOI: https://doi.org/10.1007/s10015-004-0299-3

1

2004

Manoukis NC, Lee Y, Vallejo E, Taylor CE. Detecting recurrent extinction in a metapopulations of Anopheles gambiae: preliminary results using simulation. Proceedings of the 6th WSEAS International Conference on Algorithm, Scientific Computing, Modeling and Simulation. WSEAS TRANSACTIONS on SYSTEMS, 3(4): 1623-1628. [PDF]

“INDEXED” means the article has gone through peer-review process and thus available in search engine such as PUBMED.

 

Extension Publications

2023

Blosser I, Lee Y. “Mosquitos Asombrosos" (children's book, Spanish)

paperback ISBN 9781312478022 [Lulu link]

2023

Blosser I, Lee Y. “Amazing Mosquitoes” (children’s book, paperback + hardcover)

Paperback: ISBN 9781365243462 [Lulu link]

Hardcover: ISBN 9781365175671 [Lulu link]

2023

Romero-Weaver AL, Reeves LE, Riles MT, Lee Y, Giordano BV. A concise guide on the bionomics and key morphological characteristics for identifying Culex coronator (Dyar & Knab, 1906) – an invasive mosquito species from neotropics. Ask IFAS. ENY-2093. DOI: doi.org/10.32473/edis-IN1385-2023

2023

Romero-Weaver AL, Riles MT, Sloyer K, Lee Y, Campbell LP, Giordano BV. A concise guide on the bionomics and key morphological characteristics for identifying Aedes pertinax (Grabham, 1906) – an invasive mosquito species from neotropics. Ask IFAS. Ask IFAS. ENY2100 DOI: doi.org/10.32473/edis-IN1405-2023

2022

Lee Y. Aedes mosquito posters. UF/IFAS Blogs. https://blogs.ifas.ufl.edu/fmel/2022/09/16/aedes-mosquito-posters/

2021

Caragata EP, Lee Y, Buckner EA. Genetically Modified Mosquitoes. Ask IFAS. University of Florida. 2021. ENY2066 DOI: doi.org/10.32473/edis-IN1326-2021

 

Other Research Publications

2003

[Proceedings] Kobele GM, Riggle J, Collier TC, Lee Y, Lin Y, Yao Y, Taylor CE, Stabler EP. Grounding as Learning. Proceedings of the Workshop on Language Evolution.

2003

[Proceedings] Stabler EP, Collier TC, Kobele GM, Lee Y, Lin Y, Riggle J, Yao Y, Taylor CE. The learning and emergence of mildly context sensitive languages. ECAL 2003: European Conference on advances in Artificial Life, 2801: 525-534.

2016

[Poster] Yamasaki YK, Nieman CC, Chang AN, Collier TC, Main BJ, Lee Y. Improved tools for genomic DNA library construction of small insects. F1000Res. 5:211. doi: 10.7490/f1000research.1111322.1

2016

[Poster] Collier TC, Nieman CC, Chiu JC, Slatkin M, Marshall JM, Yamasaki YK, Main BJ, Cornel AJ, Lanzaro GC, Lee Y. Genomic estimation of dispersal for African malaria vectors. UC Davis Signature Research in Genomics Symposium.

2018

October 10, [POSTER] Blosser E, Bargielowski I, Lee Y, Lanzaro G. Interspecific mating in invasive Aedes species in California. The 48th Annual Conference of the Society for Vector Ecology. Yosemite, CA

2018

October 10, [POSTER] Schmidt H, Lee Y, Hanemaaijer M, Kirstein O, Marshall J, Collier T, Slatkin M, Cornel A, Lanzaro G. Population genomic evaluation of Mali and the Comoros for the release of genetically engineered mosquitoes for malaria control. The 48th Annual Conference of the Society for Vector Ecology. Yosemite, CA

2018

October 10, [POSTER] Kirstein OD, Lee Y, Hanemaaijer M, Schmidt H, Weakley A, Chang A, Gripkey H, Cornel A, Lanzaro G. Interspecific introgression as a mechanism for the evolution of insecticide resistance in in African malaria vectors. The 48th Annual Conference of the Society for Vector Ecology. Yosemite, CA

2018

October 10, [POSTER] Hanemaaijer M, Gripkey H, Weakley A, Person K, Schmidt H, Kirstein O, Lee Y, Cornel A, Lanzaro G. How did Anopheles coluzzii from Sao Tome and Principe acquire the kdr allele? The 48th Annual Conference of the Society for Vector Ecology. Yosemite, CA

2019

June 8, 2019. [POSTER] Bargielowski I, Lee Y, Blosser E, Collier T, Cornel A, Lanzaro GC. Genomic adaptation in Aedes aegypti in California. Bay Area Population Genomics Group Meeting, Stanford, CA.

2019

June 8, 2019. [POSTER] Houston P, Bargielowski I, Blosser E, Weakley A, Gripkey H, Person K, Barker C, Main B, Cornel A, Lee Y, Lanzaro GC. Development of arboviruses detection assay using viral genome data. Bay Area Population Genomics Group Meeting, Stanford, CA.

2019

September 22-26. [POSTER] Blosser E, Bargielowski I, Lee Y, Collier T, Cornel AJ, Lanzaro G. Genomic adaptation in Aedes aegypti in California. The 49th Annual Conference of the Society for Vector Ecology. Puerto Rico

2019

September 22-26. [POSTER] Lee Y, Collier T, Bargielowski I, Blosser E, Cornel AJ, Lanzaro G. Population structure of Aedes aegypti in the Dutch Caribbean. The 49th Annual Conference of the Society for Vector Ecology. Puerto Rico

2019

November 6. [POSTER] Gripkey HF, Campos M, Lumley A, Lee Y. Improved tools for genomic DNA library construction of small insects (2019 Update). The Bay Area Population Genomics Meeting XVIII. Berkeley, CA.

2019

[Proceedings] Lee Y, Schmidt H, Collier TC, Weakley AM, Gripkey H, Person K, Brisco K, Fonseca N, Bargielowski IE, Blosser EM, Mulligan FS, Rosario-Cruz R, Lanzaro GC, Cornel AJ. Population genomics of Aedes aegypti in California. In Proceedings and Papers of the Eighty-Seventh Annual Conference of the Mosquito and Vector Control Association of California. Dec. 2019. ISSN 1554-4974. 87(1): 23-29.

Bookchapters

2021

Schmidt H, Kirstein OD, Chen T-Y, Campbell LP, Collier TC, Lee Y*. The population genomics of Anopheles gambiae species complex: progress and prospects. Population Genomics: Insects. Rajora OP, Dupuis J (eds). https://link.springer.com/chapter/10.1007/13836_2021_92

2021

Lee Y, Saavedra-Rodriguez K, Chen T-Y, Campbell LP, Smartt CT. The population genomics of Aedes aegypti: progress and prospects. Population Genomics: Insects. Rajora OP, Dupuis J (eds). https://link.springer.com/chapter/10.1007/13836_2021_93

2017

Dorn PL, Justi S, Krafsur ES, Lanzaro GC, Cornel AJ, Lee Y, Hill CA. “Chapter 15: Genetics of major insect vectors” in Genetics and Evolution of Infectious Diseases, 2nd edition, Tibayrenc M (ed), Elsevier. https://doi.org/10.1016/B978-0-12-799942-5.00015-9

2013

Lanzaro GC and Lee Y: Speciation in Anopheles gambiae - The Distribution of Genetic Polymorphism and Patterns of Reproductive Isolation Among Natural Populations., Sylvie Manguin, (ed), Anopheles mosquitoes - New insights into malaria vectors, InTech, 173-196. http://dx.doi.org/10.5772/56232

2008

Lee Y, Collier TC, Taylor CE, Stabler EP: Cohesion of languages in grammar networks, J Shamma, (ed), Cooperative Control of Distributed Multi-Agent Systems, Wiley-Interscience, Chichster, UK.

Abstracts

2008

Lee Y, Meneses CR, Fofana A, Andrianarivo AG, McAbee RD, Fondjo E, Traore SF, Cornel AJ, Lanzaro GC. Ecological and Genetic Relationship of the Forest-M Form among Chromosomal and Molecular Forms of the Malaria Vector Anopheles gambiae s.s. The 57th ASTMH Annual Meeting Abstract Book, 16.

2010

Horton AA, Souvannasang L, Lee Y, Coulibaly CA, Cornel AJ, Lanzaro GC, Luckhart S. Disease Association Mapping in Anopheles gambiae: What Is the Effect of Single Nucleotide Polymorphisms on Malaria Infection? The 59th ASTMH Annual Meeting Abstract Book, 83(5 supplement): 256.

2011

Sanford MR, Demirci B, Marsden CD, Lee Y, Cornel AJ, Lanzaro GC. Wing Size Differentiation between the Incipient Species of Anopheles gambiae s.s. and its Potential Role in Assortative Mating. The 60th ASTMH Annual Meeting Abstract Book, 85(6 supplement): 310.

2011

Trout Fryxell RT, Seifert SN, Lee Y, Lanzaro G, Cornel A. Potential Genotypic Identification of the below Ground Phenotype in the Culex pipiens Complex in California Using SNP Genotyping. The 60th ASTMH Annual Meeting Abstract Book, 85(6 supplement): 480.

2013

Marsden C, Han S, Weakley A, Kreppel K, Cornel A, Ferguson H, Lee Y, Eskin E, Lanzaro G. Genetic Diversity and Linkage Disequilibrium in the Anopheles arabiensis Genome, as Revealed by Whole Genome Sequencing. The 62nd ASTMH Annual Meeting Abstract Book, 89(5 supplement): 20.

2013

Norris LC, Lee Y, Fofana A, Lanzaro G. Dynamics Of Kdr and Speciation Island Introgression between Anopheles gambiae Molecular Forms in Southern Mali. 62nd ASTMH Annual Meeting Abstract Book, 89(5 supplement): 339.

2014

Sarah Anne J. Guagliardo, Yoosook Lee, Jacklyn Wong, Yui Yin Chu, Helvio Astete, Thomas W. Scott, Steven T. Stoddard. Aedes aegypti population structure is driven by boater traffic in the Peruvian Amazon. The 63rd ASTMH Annual Meeting Abstract Book, 91 (5 supplement): 238.

2014

Nilton B. Rodrigues, Rejane C. Simoes, Nagila F. Secundino, Yoosook Lee, Wanderli P. Tadei, Paulo F. Pimenta, Gregory Lanzaro. Association of single nucleotide polymorphisms in immune response pathways genes, and susceptibility/resistance phenotypes of Anopheles darlingi to Plasmodium vivax. The 63rd ASTMH Annual Meeting Abstract Book, 91 (5 supplement): 413.

2016

[Abstract] Jones CM, Lee Y, Collier T, Pringle JC, Carpi G, Stevenson J, Coetzee M, Muleba M, Yamasaki Y, Cornel AJ, Norris DE for the Southern Africa International Centers of Excellence for Malaria Research. Population Structure of Anopheles funestus in Southern Africa. 65th ASTMH Annual Meeting Abstract Book, 95 (5 supplement): 446.

2020

[Abstract] Mack L, Kelly T, Brisco K, Lee Y, Cornel A, Attardo G. Pairing individual resistance phenotype information with SNP data in Aedes aegypti from California. In Proceedings and Papers of the Eighty-Eighth Annual Conference of the Mosquito and Vector Control Association of California. 2020.  88(1): 76. https://www.mvcac.org/amg/wp-content/uploads/ppmv-88-01-combined-finals.pdf

2020

León TM, Sánchez HMC, Lee Y, Marshall J. New methods for modeling Anopheles gambiae s.l. movement with environmental and genetic data. ASTMH Annual Meeting. American Society of Tropical Medicine and Higyiene 103 (5 suppl): 164-165 (Abstract #588). https://www.astmh.org/getmedia/71a0e5e6-7c06-48a4-ab47-d50c4ec870a2/ASTMH-2020-Abstract-Book.pdf

2021

Lee Y. Leveraging genomics for integrated mosquito control in Dutch Caribbean islands region. Symposium on "Leveraging genomics and biotechnology for integrated pest management to address challenges of  global food security”, XXVI International Congress of Entomology, Helsinki, Finland, July 19-24, 2020 ** Accepted (Invited presentation); Meeting postponed to 2021 due to COVID-19**

 

Yoosook Lee

Yoosook Lee

Assistant Professor

Molecular Ecology, Population Genomics, Bioinformatics
yoosook.lee@ufl.edu
Honors & Awards

2023

University of Florida Global Fellows.

2022

2022 Friends of IPM ‘Pulling Together’ Award for the Mosquito BEACONS initiative (YL as the Mosquito BEACONS Board of Directors). Southern Integrated Pest Management Center.

2020

Carballar-Lejarazú et al. 2020 mentioned in "In This Issue" of PNAS September 15, 2020 https://www.pnas.org/content/117/37/22605

2018 Hanemaaijer et al. 2018 chosen as “On the Cover” article for early 2019 edition. A perspective written by Barton N on Hanemaaijer et al. 2018 on Molecular Ecology.

2016

Featured article (Main et al. 2016) on PLoS Genetics on the week of Sep. 16, 2016.

2015

 

Cover of Journal of Medical Entomology, http://jme.oxfordjournals.org/content/52/5/i1, for Lanzaro et al. 2015, JME.

2015

Research highlights on Nature and PNAS for an article, Norris et al. 2015. PNAS

2014

Featured article (Sanford et al. 2014) on F1000Research

2010

Journal of Medical Entomology 2009 Editor's Choice Award for Lee et al. 2009. JME.

2010

BioMed Central Open Data Award 2009 Winner at the 4th BioMed Central Annual Research Award, London, UK, June 10, 2010

2008

William C. Reeves New Investigator Award 3rd place winner, 2008 Mosquito and Vector Control Association of California Annual Conference. Palm Springs, CA.

2003 

Best Paper Award, 8th International conference on artificial life and robotics, Bepbu, Japan.